Working Group on the Application of the 3Rs in Regulatory Testing of Medicinal Products

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The Joint Committee for Medicinal Products for Veterinary Use/Committee for Medicinal Products for Human Use Working Group on the Application of the 3Rs in Regulatory Testing of Medicinal Products (J3RsWG) provides advice and recommendations to the Committee for Medicinal Products for Veterinary Use (CVMP) and Committee for Medicinal Products for Human Use (CHMP) on all matters relating to the use of animals and the application of the '3 R' principles (replacement, reduction and refinement) in the testing of medicines for regulatory purposes.

The Agency has also published its position on the application of the 3Rs in the testing of medicines, together with recommendations for marketing-authorisation holders on their need to comply with 3R methods in the European Pharmacopoeia:

Mandate, rules of procedure and work programme

Other J3RsWG publications

Composition

The J3RsWG consists of a core group of one or two European experts from each of the existing CVMP and CHMP Working Parties for which animal testing is relevant:

The core group also contains one member of the CVMP.

In addition to its core group, the Expert Group consists of a few experts with relevant experience.

Members

Below (in alphabetical order of surname) are the current members of the J3RsWG.  The members' declarations of interests are available in the European expert list.

  • Svein Rune Andersen
  • Tímea Barna
  • Jeremiah Gabriel Beechinor
  • Susanne Brendler-Schwaab
  • Klaus Cussler
  • Ellen-Margrethe Vestergaard (Vice-Chair)
  • Ralph Woodland
  • Barbara Zemann