Water for injection prepared by reverse osmosis

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This guideline applies to human and veterinary medicines.

Current effective version

Reflection paper

Reference numberCHMP/CVMP/28271/08
Published05/03/2008
KeywordsWater for injections, reverse osmosis, excipient, pharmacopoeia
DescriptionThis paper outlines why it is currently not considered acceptable to use reverse osmosis for the production of water for injections. In view of recent technological advancements in this field, this paper aims to stimulate discussion on this topic.


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