Viral safety of oral poliovirus vaccine (OPV)

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Position paper

Reference numberCPMP/BWP/972/98
KeywordsOral poliovirus vaccine (OPV), safety, monkey kidney cell, cell substrates, simian virus 40 (SV4), simian immunodeficiency virus (SIV), adventitious agent, inactivated polivirus vaccine
DescriptionThis document gives consideration to the safety aspects of oral polio vaccines (OPV). It covers the possibility for introducing PCR testing of OPV for viral contamination.

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