CHMP SWP conclusions and recommendations on the use of genetically modified animal models for carcinogenicity assessment

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Revision 1 - Position paper

Reference numberCPMP/SWP/2592/02 Rev. 1
KeywordsCarcinogenicity, genetically modiefied animal models, transgenic model, knockout model, ILSI/HESI study
DescriptionThis document discusses regulatory acceptance of the use of transgenic animal models for carcinogeniciy testing. It provides an assessment of the data generated by ILSI/HESI Alternatives to Caricongenicity Testing Project.

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