Background to the CPMP Position Paper on possible pre-clinical studies to investigate addiction and dependence/withdrawal related to the use of selective serotonin uptake inhibitors (SSRIs)

Current version

PDF iconPosition paper

Reference numberCPMP/2278/00
Published14/12/2000
KeywordsSelective serotonin uptake inhibitor (SSRIs), dependence, neuroadaptation, rewarding properties, addiction
DescriptionThis document defines in detail the character of pre-clinical studies to investigate addiction and dependence/withdrawal related to the use of selective serotonin uptake inhibitors (SSRIs). It gives special consideration to physical dependence, neuroadaptation and rewarding properties of SSRIs.


Related content


How useful was this page?

Add your rating