Clinical development of medicinal products intended for the treatment of pain

Current version

PDF iconAdopted guideline

Reference numberEMA/CHMP/970057/2011
Published22/01/2016
Effective from01/07/2017
KeywordsPain, neuropathic, nociceptive, chronic, acute, analgesia
DescriptionThis guideline is intended to provide guidance on the clinical development of new medicinal products for the treatment of pain. It replaces and updates the separate guidelines on neuropathic and nociceptive pain (superseeded documents below).


Document history

First version

Current version

PDF iconAdopted guideline

PDF iconDraft guideline - Corr. 1


PDF iconDraft guideline


PDF iconConcept paper

In operation: 01/07/2017-present

Published: 21/12/2015


Published: 30/05/2013


Published: 29/09/2011

Document to be superseded

PDF iconAdopted guideline


PDF iconOverview of comments


PDF iconDraft guideline

In operation: 31/06/2007–present


Published: 24/01/2007


Published: 26/01/2006

Document to be superseded PDF iconAdopted guideline In operation: 01/05/2003–present


Related content


How useful was this page?

Add your rating