Working Group on the Application of the 3Rs in Regulatory Testing of Medicinal Products

The Joint Committee for Medicinal Products for Veterinary Use (CVMP)/Committee for Medicinal Products for Human Use (CHMP) Working Group on the Application of the 3Rs in Regulatory Testing of Medicinal Products (Joint 3Rs Working Group) provides advice to the CVMP and the CHMP on all matters concerning the use of animals in regulatory testing of medicines with particular focus on the application of the so-called 3Rs principles (replace, reduce and refine).

The 3Rs stand for:

  • replacing the use of animals with non-animal methods where possible;
  • reducing the number of animals used to a minimum while still obtaining scientifically valid results;
  • refining practices to minimise the stress and improve the welfare of study animals used for regulatory purposes.

For more information on how the European Medicines Agency (EMA) and its Joint 3Rs Working Group support the implementation of the 3Rs principles in the European Union, see:

Mandate, rules of procedure and work programme

For more information on the Joint 3Rs Working Group's responsibilities and composition, see:

Composition

The Joint 3Rs Working Group consists of:

Members

Below (in alphabetical order of surname) are the current members of the Joint 3Rs Working Group. The members' declarations of interests are available in the European expert list.

Members

  • Svein Rune Andersen
  • Tímea Barna
  • Jeremiah Gabriel Beechinor
  • Sonja Beken
  • Susanne Brendler-Schwaab (Vice-Chair)
  • Klaus Cussler
  • Ellen-Margrethe Vestergaard (Chair)
  • Ralph Woodland
  • Barbara Zemann