Assessment of the genotoxic potential of antisense oligodeoxynucleotides

Current version

PDF iconReflection paper

Reference numberCHMP/SWP/199726/04
KeywordsGenotoxicity, antisense oligonucleotides, genotoxicity tests, phosphorothioate nucleotides
DescriptionThis document discusses the potential of inducing mutations by antisense oligodeoxynucleotides. It gives recommendtation on the type of mutagenicity testing, if such is deemed necessary.

Related content

How useful was this page?

Add your rating