This content applies to human and veterinary medicines.
For more information, see:
Guidance on how to pay fees and charges levied by EMA is available for applicants and marketing authorisation holders.
This document is updated in line with the New Fee Regulation, applicable as of 1 January 2025.
As of this date, EMA requires fees or charges to be paid in their entirety before it can provide the following services:
These are also known as services subject to prepayment.
EMA advises customers to be vigilant about phishing attempts involving emails appearing to be from EMA. If in doubt, please contact EMA's accounts team at accountsreceivable@ema.europa.eu to verify the authenticity of any EMA correspondence.
Applicants and marketing authorisation holders being levied a fee by EMA for the first time should contact EMA's accounts team to request a customer account number.
The customer account number is a unique reference number with EMA for financial matters. It is quoted on the invoice and all the related financial correspondence received from EMA. Applicants and marketing-authorisation holders should quote their account number with EMA on each procedural submission cover letter and in all correspondence related to financial matters.
EMA issues invoices to the customer's billing address held on EMA's file at the date when the fee becomes due.
Invoices for marketing-authorisation fees contain:
Invoices for pharmacovigilance fees contain:
Applicants and marketing authorisation holders requiring a purchase order number or similar references on their invoice are strongly encouraged to add EMA to their purchase order exemption list as a decentralised body of the European Union (EU).
Alternatively, applicants and marketing authorisation holders can issue a standing (blanket) purchase order covering all marketing authorisation and / or pharmacovigilance fees levied by EMA for a given period. They should provide such reference to accountsreceivable@ema.europa.eu.
The reference can also be provided at the point of e-submitting a procedure to EMA, with the exception of certain procedures.
Please note that EMA will not accept disputes on the grounds that a purchase order number is not provided. The use of the purchase order system is an internal control process of the applicant. It cannot be used as reason to withhold the payment of EMA’s fees.
EMA has implemented an online invoicing portal to enable customers to:
To register with the EMA invoicing portal, please select 'Register now' on the portal log-in page https://fees.ema.europa.eu/bd/public/zindex.jsp and follow the instructions on screen.
Payments must be made by the payable date indicated on the invoice by bank transfer.
The payment by bank transfer must be made net of all bank charges, withholding taxes and any other deductions, in euro and by means of a transfer to EMA's bank account:
ABN AMRO Bank N.V.
IBAN: NL33 ABNA 0837 2865 06
SWIFT: ABNANL2A
Payments should make clear reference to the invoice number. Alternatively, in the case of single remittance for multiple invoices, a remittance advice must be sent to EMA, by email to accountsreceivable@ema.europa.eu.
Any query arising on the invoice must be notified to EMA as soon as possible via the EMA invoicing portal.
Please refer to EMA's guidance to marketing authorisation holders and applicants on how to pay fees levied by EMA, section 3.