NexoBrid - supply shortage

Shortage resolved

concentrate of proteolytic enzymes enriched in bromelain
ShortageHuman

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Shortage information

A problem with a quality control test used during the manufacture of NexoBrid 5 g led to supply shortages from October 2025. The issue has been resolved, and NexoBrid is now being distributed again. The shortage has ended, and the information and recommendations provided during the shortage no longer apply.

Key facts

Medicines affected
NexoBrid
Supply shortage status
Shortage resolved
International non-proprietary name (INN) or common name
concentrate of proteolytic enzymes enriched in bromelain
Therapeutic area (MESH)
Debridement
Availability of alternatives
No

Key dates

First published
Last updated

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