CHMP SWP conclusions and recommendations on the use of genetically modified animal models for carcinogenicity assessment - Scientific guideline

This document discusses regulatory acceptance of the use of transgenic animal models for carcinogeniciy testing. It provides an assessment of the data generated by ILSI/HESI Alternatives to Caricongenicity Testing Project.

Keywords: Carcinogenicity, genetically modified animal models, transgenic model, knockout model, ILSI/HESI study

Current version

CHMP SWP conclusions and recommendations on the use of genetically modified animal models for carcinogenicity assessment - Revision 1

Adopted Reference Number: CPMP/SWP/2592/02 Rev 1