Antimicrobial resistance in veterinary medicine

Combatting the threat of antimicrobial resistance, particularly resistance to antibiotics, is a high priority for the European Medicines Agency (EMA) and the European medicines regulatory network. In veterinary medicine, EMA is promoting prudent use of antimicrobials in animals, collecting data on the use of veterinary antimicrobials in the European Union (EU), and providing scientific recommendations on the use of specific antimicrobials in animals.

Antimicrobial resistance is when a microbe evolves to become more or fully resistant to antimicrobials which previously could treat it. Antimicrobials include antibiotics, which kill or inhibit the growth of bacteria. For more information, see Antimicrobial resistance.

Antimicrobial use in animals can contribute to the emergence of resistant bacteria that can be transferred to humans through the food chain or direct contact. This can reduce the effectiveness of antimicrobials for treating human disease.

The emerging and steady increase in the occurrence of bacteria that are resistant to multiple antibiotics has become a global public health threat due to the lack of therapeutic options to treat certain infections in humans. After being exposed to an antimicrobial substance repeatedly, microbes can undergo changes that stop them being killed or inactivated by the treatments.

To limit the development of resistance for the benefit of animal and public health, EMA is promoting the prudent use of antimicrobials in animals and is engaged in numerous activities to address the threat arising from the use of medically important antimicrobials in food-producing animals.

Also on this topic

• Antimicrobial Sales and Use Platform
• European Sales and Use of Antimicrobials for Veterinary Medicine (ESUAvet) annual surveillance reports
• Analysis of antimicrobial consumption and resistance ('JIACRA' reports)
• European Surveillance of Veterinary Antimicrobial Consumption (ESVAC): 2009 - 2023
• Advice on impacts of using antimicrobials in animals

CVMP activities related to antimicrobials

A report on CVMP activities on antimicrobials is available including ongoing and planning EMA activities on this topic. 

The report is in line with:

• European medicines agencies network strategy to 2028 (theme 4)
• EU's One Health approach

It builds on the previous CVMP strategy on antimicrobials which concluded in 2025.

More information on the report as well as on CVMP's current and previous antimicrobial strategies is available via the link below:

• CVMP activities related to antimicrobials

For more information, see:

• Veterinary Medicinal Products Regulation
• European medicines agencies network strategy
• One Health approach

Monitoring veterinary antimicrobial consumption

Monitoring antimicrobial consumption is crucial for identifying risk factors that contribute to the development and spread of antimicrobial resistance in food-producing animals. 

Collecting accurate data on the use of antibiotics is an essential first step in developing and monitoring policies on its responsible use in the Member States.

For more information, see:

• European Sales and Use of Antimicrobials for Veterinary Medicine (ESUAvet) annual surveillance reports
• Antimicrobial Sales and Use Platform
• European Surveillance of Veterinary Antimicrobial Consumption (ESVAC): 2009 - 2023

Analysis of antimicrobial consumption and resistance

EMA works closely with the European Food Safety Authority (EFSA) and the European Centre for Disease Prevention and Control (ECDC) to analyse the potential relationship between the consumption of antimicrobials by humans and animals and the occurance of antimicrobial resistance. The agencies deliver their findings in joint inter-agency antimicrobial consumption and resistance analysis (JIACRA) reports.

Recommendations on the use of antibiotics in animals

EMA supports the European Commission's action plan against the rising threats from antimicrobial resistance by providing scientific input and advice on impacts of using antimicrobials in animals in partnership with other relevant EU bodies. This includes a joint opinion with EFSA on measures to reduce the need to use antimicrobial agents in animal husbandry (also known as the 'RONAFA' opinion).

Earlier reports published jointly by EMA and European bodies including ECDC, EFSA and the European Commission's Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR) have emphasised the need for the prudent use of antibiotics in animals and the role of basic hygiene, and called for strengthened surveillance of resistance, the development of new antimicrobials and new strategies to combat the spread of resistance:

• Joint scientific report of the European Centre for Disease Prevention and Control, European Food Safety Authority and European Medicines Agency on meticillin-resistant Staphylococcus aureus (MRSA) in livestock, companion animals and food (16/06/2009)
• Joint opinion on antimicrobial resistance focused on zoonotic infections (10/2009)

Page update history

An update log is available to show the date and summary of changes to this webpage. It does not include updates to linked documents or minor edits like typos or broken link fixes.

The tracking of updates begins in July 2026.

See update history

10 July 2026

• Section on 'CVMP activities related to antimicrobials' updated to include information on a report on CVMP activities related to antimicrobials