On 25 July 2019, orphan designation EU/3/19/2180 was granted by the European Commission to Aprea Therapeutics AB, Sweden, for 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one (also known as APR-246) for the treatment of myelodysplastic syndromes.
|Disease / condition||
Treatment of myelodysplastic syndromes
|Date of first decision||
|EU designation number||
Review of designation
Sponsor's contact details
For contact details of patients’ organisations whose activities are targeted at rare diseases, see:
European Organisation for Rare Diseases (EURORDIS), a non-governmental alliance of patient organisations and individuals active in the field of rare diseases.
Orphanet, a database containing information on rare diseases, which includes a directory of patients’ organisations registered in Europe.