Use of heat treatment to inactivate endogenous retroviruses in live immunological veterinary medicinal products - Scientific guideline

This document outlines the data requirements to be submitted by the marketing authorisation holder to introduce a heat treatment to inactivate endogenous retroviruses in the active substance for the production of live viral for immunological veterinary medicinal products (IVMPs) and to show the absence of negative impact of this treatment on the IVMP.

Keywords: Endogenous retrovirus, immunological veterinary medicinal product (IVMP), heat treatment