Use of herbal medicinal products containing toxic, unsaturated pyrrolizidine alkaloids (PAs)

This document describes chemical, toxicological, pharmacological and pharmacokinetic properties of unsaturated pyrrolizidine alkaloids (PAs). It sets out recommendations for the oral and cutaneous use of herbal medicinal products and traditional herbal medicinal products containing PAs.

Keywords: Herbal medicinal products, pyrrolizidine alkaloids

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