Use of methyl- and propylparaben as excipients in human medicinal products for oral use - Scientific guideline

This reflection paper addresses methyl- and propylparaben, as those are the parabens predominantly used in oral pharmaceutical formulations. The focus of this document is on possible endocrine-disrupting effects in humans.

Keywords: methylparaben, propylparaben, excipients, preservatives in medicinal products, paediatric use, endocrine disruptors