Clinical investigation of medicinal products in the treatment of depression

Current effective version

PDF iconRevision 2 - Adopted guideline

Reference numberCHMP/185423/2010 Rev. 2
Published30/05/2013
Effective from01/12/2013
KeywordsMajor depression, major depressive episode, partial response, treatment resistance, suicidal thoughts, suicidal behaviour, suicide, acute treatment, maintenance treatment, recurrence prevention
DescriptionThis document provides guidance on the development of medicinal products for acute and long-term treatment of major depressive disorder


Document history

Revision 3

In progress

PDF iconConcept paper

Published: 18/11/2016

Deadline for comments: 28/02/2017

Revision 2

Current version

PDF iconAdopted guideline


PDF iconDraft guideline


PDF iconConcept paper

In operation: 01/12/2013–present


Published: 11/10/2011


Published: 19/02/2009

Revision 1 PDF iconAdopted guideline In operation: 01/10/2002–30/11/2013


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