Evaluation of control samples for non-clinical safety studies: checking for contamination with the test substance - Scientific guideline

HumanScientific guidelines

On Monday, 12 January 2026, between 07:00 and 10:00 CET (Amsterdam time), this website will be unavailable due to scheduled maintenance.

This document provides guidance on assaying the levels of test substance in samples from control animals in non-clinical safety studies.

Keywords: Control samples, non-clinical, safety studies, contamination

Current effective version

Guideline on the evaluation of control samples in nonclinical safety studies: checking for contamination with the test substance

Adopted Reference Number: CPMP/SWP/1094/04 Legal effective date: 01/09/2005

English (EN) (37.89 KB - PDF)

First published: 17/03/2005 Last updated: 17/03/2005