Poorly extractable and/or non- radiolabelled substances - Scientific guideline

This document provides a guidance on how to perform OECD 307: Aerobic and anaerobic transformation in soil study with poorly extractable and/or non-radiolabelled substances.

Keywords: OECD 307, non-extractable residues, bound residues, veterinary medicinal product (VMP), degradation in manure

Current effective version

Reflection paper on poorly extractable and/or non-radiolabelled substances

Adopted Reference Number: EMA/CVMP/ERA/349254/2014 Rev.1 Summary:

Some of the active substances used in veterinary medicines have the propensity to strongly adsorb to environmental matrices.

Document history

Overview of comments received during the public consultation on ‘Reflection paper on poorly extractable and/or non-radiolabelled substances'

Reference Number: EMA/CVMP/ERA/603511/2015

Draft reflection paper on poorly extractable and or non-radiolabelled substances

Draft: consultation closed Consultation dates: 20/03/2015 to 31/08/2015 Reference Number: EMA/CVMP/ERA/349254/2014 Summary:

Some of the active substances used in veterinary medicines have the propensity to strongly adsorb to environmental matrices.