Assessment of the genotoxic potential of antisense oligodeoxynucleotides - Scientific guideline
Human
Scientific advice
This document discusses the potential of inducing mutations by antisense oligodeoxynucleotides. It gives recommendtation on the type of mutagenicity testing, if such is deemed necessary.
Keywords: Genotoxicity, antisense oligonucleotides, genotoxicity tests, phosphorothioate nucleotides