EU/3/21/2502: Orphan designation for the treatment of small cell lung cancer

Humanised IgG1 monoclonal antibody against SEZ6 linked to N-acetyl-calicheamicin

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This medicine was designated as an orphan medicine for the treatment of small cell lung cancer in the European Union (EU) on 15 October 2021.

This means that the developer will receive scientific and regulatory support from EMA to advance their medicine to the stage where they can apply for a marketing authorisation.

Orphan designation does not mean the medicine is available or authorised for use. All medicines, including designated orphan medicines, must be authorised before they can be marketed and made available to patients in the EU.

During the medicine's development, doctors may be able to enrol patients in clinical trials investigating the medicine. For information on ongoing clinical trials in the EU, see:

Key facts

Active substance
Humanised IgG1 monoclonal antibody against SEZ6 linked to N-acetyl-calicheamicin
Intended use
Treatment of small cell lung cancer
Orphan designation status
EU designation number
Date of designation

AbbVie Deutschland GmbH & Co. KG
67061 Ludwigshafen Am Rhein
Tel. +49 621 589 3382

Update history

July 2023Please note that this product was withdrawn from the Union Register of orphan medicinal products in July 2023 on request of the Sponsor.

Documents related to this orphan designation evaluation

Patients' organisations

For contact details of patients’ organisations whose activities are targeted at rare diseases, see:

  • European Organisation for Rare Diseases (EURORDIS), a non-governmental alliance of patient organisations and individuals active in the field of rare diseases.

  • Orphanet, a database containing information on rare diseases, which includes a directory of patients’ organisations registered in Europe.

EU register of orphan medicines

The list of medicines that have received an orphan designation in the EU is available on the European Commission's website:

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